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KMID : 0357520140370020125
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Journal of Radiological Science and Technology
2014 Volume.37 No. 2 p.125 ~ p.134
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Evaluation of Photoneutron Dose for Prostate Cancer Radiation Therapy by Using Optically Stimulated Luminescence Dosimeter (OSLD)
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Lee Joo-Ah
Back Geum-Mun
Kim Yeon-Soo
Son Soon-Yong
Choi Kwan-Woo
Yoo Beong-Gyu
Jeong Hoi-Woun
Jung Jae-Hong
Kim Ki-Won
Min Jung-Whan
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Abstract
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This study is to provide basic information regarding photoneutron doses in terms of radiation treatment techniques and the number of portals in intensity-modulated radiation therapy (IMRT) by measuring the photoneutron doses. Subjects of experiment were 10 patients who were diagnosed with prostate cancer and have received radiation treatment for 5 months from September 2013 to January 2014 in the department of radiation oncology in S hospital located in Seoul. Thus, radiation treatment plans were created for 3-Dimensional Conformal Radiotherapy (3D-CRT), Volumetric-Modulated Arc Radiotherapy (VMAT), IMRT 5, 7, and 9 portals. The average difference of photoneutron dose was compared through descriptive statistics and variance analysis, and analyzed influence factors through correlation analysis and regression analysis. In summarized results, 3D-CRT showed the lowest average photoneutron dose, while IMRT caused the highest dose with statistically significance (p <.01). The photoneutron dose by number of portals of IMRT was $4.37{pm}1.08mSv$ 수식 이미지 in average and statistically showed very significant difference among the number of portals (p <.01). Number of portals and photoneutron dose are shown that the correlation coefficient is 0.570, highly statistically significant positive correlation (p <.01). As a result of the linear regression analysis of number of portals and photoneutron dose, it showed that photoneutron dose significantly increased by 0.373 times in average as the number of portals increased by 1 stage. In conclusion, this study can be expected to be used as a quantitative basic data to select an appropriate IMRT plans regarding photoneutron dose in radiation treatment for prostate cancer.
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KEYWORD
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Optically Stimulated Luminescence Dosimeters (OSLD), Number of portal, photo nuclear reaction, Radiation treatment techniques
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